Off-Target Development Webinar

Off-target safety assessment of biologics, generating IND enabling data and data to aid lead selection

 

 

This webinar, in collaboration with NanoMab Technology, discusses NanoMab Technology’s experiences with off-target safety assessment of biologics, generating IND enabling data and data to aid lead selection.

The presentations cover:

  • Understanding how the specificity data generated with Cell Microarray screening is used in lead candidate selection and safety assessment;
  • Learning how IND-enabling specificity data supports submissions to regulators as either an adjunct to, or alternative to, tissue cross reactivity studies; and
  • Discussing more about identifying and mitigating the risk of clinical toxicity caused by off-target effects of antibodies and related molecules

Featured presentations:

“Specificity screening of antibodies and related molecules using human cell microarray technology.”

Mark Aspinall-O’Dea, Retrogenix Limited

“The use of off target Screening for Radioimmunoconjugates.”

Nicholas Wong, NanoMab Technology Limited

Why use Retrogenix?

Ensuring that a novel biotherapeutic is specific to its intended target is undoubtedly advantageous when selecting promising lead candidates, however, it becomes vital when assessing potential safety implications prior to clinical studies.

Retrogenix specificity screening data has been readily accepted in applications for clinical trials and marketing approval in the US, Europe, China & Japan. Further details can be found in our case study using the link below. Or, to find out more, please get in touch with a member of our team.

 

Retrogenix data in regulatory submissions

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    I have greatly enjoyed working with you all on this project, it ran seamlessly and I am grateful for the responsiveness, communication and high-quality work from your team. I would not hesitate to perform studies in the future, and will highly recommend Retrogenix to my colleagues for their research needs.
    Kathy Whiteman, Senior Scientist, Unum Theraputics
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    The University of Copenhagen
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