“On-target development – Specificity screening of biotherapeutics”

Recording of July 2020 webinar

Featured presentations:

“True specificity is a critical development characteristic in therapeutic antibody development” Jonny Finlay, PhD – CEO, UltraHuman Limited

“Off-target Screening: A Pharma Industry Perspective” Martin Scott, PhD – Scientific Leader and Associate Fellow, GSK

“Cell Microarray technology in specificity screening” Nick Brown, MSc – Retrogenix Limited

  • Understand how data generated with Cell Microarray screening is used in lead selection and safety assessment
  • Explore how specificity data supports IND submissions as either an adjunct to, or replacement for, tissue cross reactivity studies
  • Learn more about identifying and mitigating the risk of clinical toxicity caused by off-target effects of monoclonal antibodies.

Why use Retrogenix?

Ensuring that a novel biotherapeutic is specific to its intended target is undoubtedly advantageous when selecting promising lead candidates, however, it becomes vital when assessing potential safety implications prior to clinical studies.

Retrogenix specificity screening data has been readily accepted in applications for clinical trials and marketing approval in the US, Europe, China & Japan. Further details can be found in our case study using the link below. Or, to find out more, please get in touch with a member of our team.


Retrogenix data in regulatory submissions

Get In Touch

    We are delighted with the work that Retrogenix has done for us. Their technology has been extremely useful in identifying and confirming the cell surface interaction partners for our antibodies and other protein ligands. The work is always carried out to a high quality standard and turned around in good time.
    Dr Ralph Minter, Fellow - Antibody Discovery and Protein Engineering – Technology, MedImmune
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